Thursday, March 22, 2018 at 12:00 PM
This grand round has already taken place.
March 22nd, 2018 1.00 AMA PRA Category 1 Credit Hours
Description
The C. elegans anchor cell (green), breaches the surrounding basement membrane (magenta) during larval development to initiate the uterine-vulval connection, allowing adult nematodes to passage eggs to the external environment. We use this simple model system to understand at single-cell resolution how cell's acquire and maintain an invasive phenotype.
Dates and Times
Start: 3/22/2018 12:00 PM
End: 3/22/2018 1:00 PM
Objectives
1. Introduce an invertebrate model system for studying the acquisition of invasive cellular behavior - C. elegans anchor cell invasion into the vulval epithelium during nematode development.
2. Explain how the power of this simple system has identified a key dichotomy in invasive behavior, revealing that cells may be unable to adopt an invasive phenotype and proliferate simultaneously.
3. Discuss the implications of this result in the context of cancer metastasis.
Speakers
Location
Pathology Classroom
Basic Science Tower
Level 9 Room 145
Stony Brook, NY 11950
Accreditation
The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) ™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.
Need help with this Grand Round Session?
Please contact the Grand Round coordinator listed below:
Leslie Moehringer
Department: Pathology
Phone: (631) 444-5931
Email: Leslie.Moehringer@stonybrookmedicine.edu