Wednesday, March 6, 2019 at 12:00 PM
This grand round has already taken place.
March 6th, 2019 1.00 AMA PRA Category 1 Credit Hours
Description
Seminar discussing recent advances in In Vivo drug activity
Dates and Times
Start: 3/6/2019 12:00 PM
End: 3/6/2019 1:00 PM
Objectives
- Introduce reasons for very high attrition in the development of new drugs.
- Understand the difference between thermodynamics and kinetics of drug-target interactions.
- Recognize that drug selectivity has two components: thermodynamic and kinetic.
- Demonstrate that dosing frequency can be reduced using drugs that dissociate slowly from their targets thereby improving safety.
- Introduce PK/PD models that link target engagement with drug concentration (PK) and drug efficacy (PD).
- Learn about target vulnerability.
Speakers
Location
Stony Brook University Medical Center
101 Nicolls Rd
HSC, L3, 066 Conference Room - Family, Population & Preventive Medicine
Stony Brook, NY 11794
Accreditation
The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) ™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.
Need help with this Grand Round Session?
Please contact the Grand Round coordinator listed below:
Robin Avidor
Department: Radiation Oncology
Phone: (631) 444-7770
Email: robin.avidor@stonybrookmedicine.edu