Thursday, January 16, 2020 at 12:00 PM
This grand round has already taken place.
Description
I will discuss the pancreatic cancer microenvironment and metabolic interactions between different cells present within pancreatic tumors . This will mainly focus on our use of metabolomics techniques to identify crosstalk interactions and the consequences of these exchanges on therapy resistance. I will also briefly discuss some recent work identifying roles for metabolism in tumorigenesis.
Dates and Times
Start: 1/16/2020 12:00 PM
End: 1/16/2020 1:00 PM
Objectives
Objectives
1. Tumors exist as a complex environment with dynamic metabolic interactions between various cell populations.
2. Macrophages that are polarized by cancer cells provide chemoresistance through release of pyrimidine nucleosides, and inhibit cytotoxic T cells through arginine depletion.
3.Cancer cells are metabolically heterogeneous and can provide support across populations through metabolite exchange
Speakers
Location
Pathology level 9 BST-145
100 Nicolls Rd
BST-145 Level 9
Stony Brook, NY 11794
Accreditation
The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) ™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.
Need help with this Grand Round Session?
Please contact the Grand Round coordinator listed below:
Mary LoBiondo
Department: Pathology
Phone: (631) 444-3000
Email: mary.lobiondo@stonybrookmedicine.edu