Metabolism Drives Therapy Resistance and Shapes Pancreatic Tumorigenesis

Pathology Grand Rounds

Thursday, January 16, 2020 at 12:00 PM


This grand round has already taken place.


Pathology level 9 BST-145 - Stony Brook, NY
January 16th, 2020
1.00 AMA PRA Category 1 Credit Hours

Description

I will discuss the pancreatic cancer microenvironment and metabolic interactions between different cells present within pancreatic  tumors . This will mainly focus on our use of metabolomics techniques to identify crosstalk interactions and the consequences of these exchanges on therapy resistance. I will also briefly discuss some recent work identifying roles for metabolism in tumorigenesis.

Dates and Times

Start: 1/16/2020 12:00 PM
End: 1/16/2020 1:00 PM

Objectives

Objectives

1. Tumors exist as a complex environment with dynamic metabolic interactions between various cell populations.
2. Macrophages that are polarized by cancer cells provide chemoresistance through release of pyrimidine nucleosides, and inhibit cytotoxic T cells through arginine depletion.
3.Cancer cells are metabolically heterogeneous and can provide support across populations through metabolite exchange

Speakers

  • Dr. Christopher Halbrook
    • Metabolism Drives Therapy Resistance and Shapes Pancreatic Tumorigenesis

Location

Pathology level 9 BST-145
100 Nicolls Rd
BST-145 Level 9
Stony Brook, NY 11794

Accreditation

The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) . Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Give us a call
(631) 444-2094
Office of Continuing Medical Education
Renaissance School of Medicine at Stony Brook University
HSC, Level 2, Room 142
Stony Brook, New York 11794-8222