Understanding target vulnerability and kinetics in predictions of drug activity.
Dates and Times
Start: 4/13/2021 11:00 AM
End: 4/13/2021 12:00 PM
1. Participants should be able to understand the role of both thermodynamics and kinetics in controlling in vivo drug-target occupancy.
2. Reasons for failure of drug candidates in clinical trials including insufficient therapeutic window.
3. Predicting the efficacy of drugs that bind to Bruton's tyrosine kinase.
4. Pharmacokinetic/pharmacodynamic models that integrate drug-target kinetics into predictions of drug activity.
5. An understanding of target vulnerability.
The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) ™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.