Tumor Suppressor p53 and Its Mutants In Cancer Metabolism

Pathology Cancer Center Grand Rounds

Thursday, December 2, 2021 at 12:00 PM


Grand Round starts in:

Online Streaming
December 2nd, 2021
1.00 AMA PRA Category 1 Credit Hours

Description

p53 plays a key role in tumor suppression. The tumor suppressive function of p53 has long been attributed to its ability to induce apoptosis, cell cycle arrest and senescence. Interestingly, recent studies have suggested that other functions of p53 also contribute to its role as a tumor suppressor, such as its function in metabolic regulation. p53 is the most frequently mutated gene in human cancers. Many mutant p53 proteins display gain-of-function (GOF) activities in cancer cells, including driving metabolic reprogramming, to promote cancer progression. Further understanding of p53 and its GOF mutants in metabolism will provide new opportunities for cancer therapy. I will summarize our recent studies on p53 and its GOF mutants in metabolic regulation.

Dates and Times

Start: 12/2/2021 12:00 PM
End: 12/2/2021 1:00 PM

Objectives

  1. Tumor suppressor p53 signaling
  2. Cancer metabolic reprogramming
  3. Protein modifications

Speakers

  • Dr. Zhaohui Feng
    • Tumor Suppressor p53 and Its Mutants In Cancer Metabolism

Accreditation

The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) . Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Need help with this Grand Round Session?

Please contact the Grand Round coordinator listed below:

Nancy Strein
Department: Pathology
Phone: (631) 444-3000
Email: nancy.strein@stonybrookmedicine.edu

Give us a call
(631) 444-2094
Office of Continuing Medical Education
Renaissance School of Medicine at Stony Brook University
HSC, Level 2, Room 142
Stony Brook, New York 11794-8222