Pathology Cancer Center Grand Rounds

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May

Pancreatic Disease: Progression From Pancreatitis to Cancer

Pathology Cancer Center Grand Rounds

12:00 PM

Online Streaming

1.00 Credit Hour(s)

My research area is focused on investigating the mechanisms of early pancreatic neoplasia and progression toward pancreatic cancer. Research from my group has demonstrated that KLF5 is an important regulator of acinar-to-ductal metaplasia (ADM) and mPanIN formation. Its deletion abrogates the pro-oncogenic effects of KRAS activating mutations alone or in the context of acute injury. Importantly, we showed that depletion of KLF5 increases expression of N-Myc Downstream-Regulated Gene 2 (NDRG2), a...

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