Update on Acute Myeloid Leukemia

Dates and Times

Start: 10/29/2025 8:00 AM
End: 10/29/2025 9:00 AM

Objectives

1. Recognize acute myeloid leukemia (AML) emergencies, particularly acute promyelocytic leukemia (APL), and understand the importance of immediate tretinoin (ATRA) initiation when APL is suspected.

2. Understand the role of cytogenetic analysis and genetic mutation profiling in diagnosing and risk stratification and prognosis of non- APL AML, and how these information guide the selection of optimal treatment strategies.

3. Stay Updated with the new drug developments in AML and Identify treatment options for older or frail patients with AML, including the use of less intensive regimens (Azacitidine and Venetoclax) and targeted therapies such as IDH1, IDH2 inhibitors.

4. Recognize and manage differentiation syndrome, understanding its key clinical manifestations (fever, weight gain, hypotension, pain, hypoxia, and AKI) and associated therapies.

5. Discuss current challenges and unmet needs in managing AML patients with adverse cytogenetic or high-risk molecular mutations (e.g., TP53, ASXL1, FLT3-ITD, KRAS, NRAS) and explore ongoing areas of research and therapeutic development.

Speakers

Accreditation

The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credits ^™. Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Maintenance of Certification

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.00 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.