Tracking Clones and Cell States in Oncogenesis and Therapy Resistance

Pathology Grand Rounds

Thursday, January 29, 2026 at 12:00 PM


Grand Round starts in:

Basic Sciences Tower Level 9, Rm 140 - Stony Brook , NY
Online Streaming Available
January 29th, 2026
1.00 AMA PRA Category 1 Credit Hours

Description

Cancer develops through Darwinian clonal evolution, where somatic mutations give rise to genetically distinct subclones. Selective pressures—microenvironmental constraints, immune surveillance, and therapy—shape clonal architecture over time.

Dates and Times

Start: 1/29/2026 12:00 PM
End: 1/29/2026 1:00 PM

Objectives

1-Clones are defined by heritable genetic alterations.

2- Bulk and single-cell DNA sequencing (WGS, targeted panels) to infer clonal phylogenies.

3-Coupled scDNA–scRNA sequencing.

Speakers

  • Sydney Shaffer, PhD
    • Tracking Clones and Cell States in Oncogenesis and Therapy Resistance

Location

Basic Sciences Tower Level 9, Rm 140
101 Nicolls Rd
Stony Brook , NY 11794

Accreditation

The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credits . Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Need help with this Grand Round Session?

Please contact the Grand Round coordinator listed below:

Rachel Larin
Department: Pathology Department
Phone: (631) 444-2169
Email: rachel.larin@stonybrookmedicine.edu

Give us a call
(631) 444-2094
Office of Continuing Medical Education
Renaissance School of Medicine at Stony Brook University
HSC, Level 2, Room 142
Stony Brook, New York 11794-8222