Rapid protein depletion by the auxin-inducible degron technology

Pathology Grand Rounds

Monday, October 21, 2019 at 12:00 PM


This grand round has already taken place.


Pharmacology conference room BST level 8 R180 - Stony Brook, NY
October 21st, 2019
1.00 AMA PRA Category 1 Credit Hours

Description

Genetic perturbation is a powerful way to analyze the function of proteins in vivo. For this purpose, we pioneered to develop the auxin-inducible degron (AID) technology (Nishimura et al, Nat. Meth., 2009). By combining with CRISPR-based genome editing, it is now possible to generate AID conditional mutants of human cells (Natsume et al., Cell Reports, 2016; Yesbolatova et al. Methods, 2019). I would like to share the history as well as our recent improvements.

Dates and Times

Start: 10/21/2019 12:00 PM
End: 10/21/2019 1:00 PM

Objectives

1) To give an introduction on  the history, concepts and methods of the auxin-inducible degron (AID) technology.


2) To discuss recent improvements in auxin-inducible degron (AID) technology.


3) To review auxin-inducible degron (AID) technology .

Speakers

  • Dr. Masato Kanemaki
    • Rapid protein depletion by the auxin-inducible degron technology

Location

Pharmacology conference room BST level 8 R180
100 Nicolls Rd
R180, BST L8
Stony Brook, NY 11794

Accreditation

The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s) . Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Give us a call
(631) 444-2094
Office of Continuing Medical Education
Renaissance School of Medicine at Stony Brook University
HSC, Level 2, Room 142
Stony Brook, New York 11794-8222