Investigating unexpected electrolyte results

Pathology Clinical Conference

Wednesday, September 3, 2025 at 12:00 PM


This grand round has already taken place.


Online Streaming
September 3rd, 2025
1.00 AMA PRA Category 1 Credit Hours

Description

We will explore how to investigate aberrant electrolyte results. Large-volume chemistry analyzers measure sodium using indirect ion-selective electrodes (ISE), while istat and blood gas analyzers use direct ISE methods.


Pseudohyponatremia can affect sodium measurement in patients with elevated protein or lipids. Alternate methods such point-of-care instruments, together with osmolality measurements, may help solve the discrepancy.

Dates and Times

Start: 9/3/2025 12:00 PM
End: 9/3/2025 1:00 PM

Objectives

1)Understand why point-of-care devices and blood gas analyzers use direct ion-selective electrodes (ISE) to measure electrolytes, while large-volume chemistry analyzers use indirect ISEs.

2)Explain how pre-analytical, analytical, and post-analytical variables can affect clinical chemistry results.

3) Describe causes of pseudohyponatremia and explain how different sodium measurement platforms impact the result.

Speakers

  • Lisa Senzel, MD
    • Investigating unexpected electrolyte results

Accreditation

The School of Medicine, State University of New York at Stony Brook, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The School of Medicine, State University of New York at Stony Brook designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credits . Physicians should only claim the credit commensurate with the extent of their participation in the activity.

Need help with this Grand Round Session?

Please contact the Grand Round coordinator listed below:

Amy Loughlin
Department: Pathology
Phone: (631) 444-3000
Email: Amy.loughlin@stonybrookmedicine.edu

Give us a call
(631) 444-2094
Office of Continuing Medical Education
Renaissance School of Medicine at Stony Brook University
HSC, Level 2, Room 142
Stony Brook, New York 11794-8222